中国组织工程研究

中国组织工程研究 ›› 2014, Vol. 18 ›› Issue (52): 8515-8519.doi: 10.3969/j.issn.2095-4344.2014.52.027

• 生物材料临床实践 clinical practice of biomaterials • 上一篇    下一篇

Neuroform3自膨式支架在弹簧圈介入栓塞宽颈前交通动脉瘤中的作用

麦麦提力•米吉提，特吾尔巴提•苏尔旦尼亚，热希旦•艾克热木，卡合尔曼•卡德尔，成晓江，买买提力•艾沙尤   

  1. 新疆医科大学第一附属医院神经外科，新疆维吾尔自治区乌鲁木齐市 830054
  • 修回日期:2014-11-13 出版日期:2014-12-17 发布日期:2014-12-17
  • 通讯作者: 买买提力?艾沙尤，主任医师，副教授，硕士生导师，新疆医科大学第一附属医院神经外科，新疆维吾尔自治区乌鲁木齐市 830054
  • 作者简介:麦麦提力?米吉提，男，1980年生，新疆维吾尔自治区乌鲁木齐市人，维吾尔族，新疆医科大学第一附属医院神经外科在读博士，主要从事脑血管病研究。 并列第一作者：特吾尔巴提?苏尔旦尼亚
  • 基金资助:

    乌鲁木齐地区维，汉民族多中心出血性脑卒中注册数据分析(2012211A071)

The application of Neuroform3 stents in the interventional embolization of wide-necked anterior communicating artery aneurysms

Maimaitili Mijiti, Tewuerbati Suerdanniya, Rexidan Aikeremu, Kaheerman Kadeer, Cheng Xiao-jiang, Maimaitili Aishayou   

  1. Department of Neurosurgery, the First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, Xinjiang Uygur Autonomous Region, China
  • Revised:2014-11-13 Online:2014-12-17 Published:2014-12-17
  • Contact: Maimaitili Aishayou, Chief physician, Associate professor, Master’s supervisor, Department of Neurosurgery, the First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, Xinjiang Uygur Autonomous Region, China
  • About author:Maimaitili Mijiti, Studying for doctorate, Department of Neurosurgery, the First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, Xinjiang Uygur Autonomous Region, China Tewuerbati Suerdanniya, Department of Neurosurgery, the First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, Xinjiang Uygur Autonomous Region, China Maimaitili Mijiti and Tewuerbati Suerdanniya contributed equally to this work.
  • Supported by:

    Uygur and Han Ethnic Multi-Center Registry Data Analysis for Hemorrhagic Stroke in Urumqi, No. 2012211A071

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摘要：

背景：近年来，采用支架辅助弹簧圈栓塞保持载瘤动脉通畅，防止弹簧圈脱入载瘤动脉，可显著提高疗效和安全性。

目的：探讨Neuroform3自膨式支架在弹簧圈介入栓塞治疗宽颈前交通动脉瘤中的应用。
方法：回顾性分析在Neuroform3自膨式支架辅助下，采用弹簧圈介入栓塞32例宽颈前交通动脉瘤患者的临床资料，其中男15例，女17例，年龄41-71岁，随访观察治疗效果及不良反应情况。

结果与结论：32例患者技术操作顺利，宽颈前交通动脉共置入32枚Neuroform3支架，弹簧圈置入顺利，释放位置满意，技术成功率达到100%。在Neuroform3支架辅助水解脱弹簧圈栓塞完成后造影显示，32枚动脉瘤完全栓塞30枚，占94%；部分栓塞2枚，占6%。术后患者恢复良好，平均住院6.3 d。32例患者术后随访3-6个月，再行全脑血管造影未见再次脑出血、脑血管栓塞或动脉瘤复发。表明在Neuroform3自膨式支架辅助下采用弹簧圈介入栓塞治宽颈前交通动脉瘤，材料与宿主生物相容性好且安全有效。


中国组织工程研究杂志出版内容重点：生物材料；骨生物材料; 口腔生物材料; 纳米材料; 缓释材料; 材料相容性；组织工程


全文链接：

关键词: 生物材料, 材料相容性, 前交通动脉瘤, Neuroform支架, 弹簧圈栓塞治疗, 并发症

Abstract:

BACKGROUND: Recently, stent-assisted coil embolization can maintain the patency of the parent artery, prevent the coil protrusion into the parent artery, and significantly improve the curative effect and safety.

OBJECTIVE: To discuss the application of Neuroform3 stents in the interventional embolization of wide-necked anterior communicating artery aneurysms.
METHODS: We retrospectively analyzed the operation outcome of 32 patients with wide-necked anterior communicating artery aneurysm who underwent interventional embolization treatment using Neuroform 3 stents, including 15 males and 17 females, aged 41-71 years. The therapeutic effects and adverse reactions were followed. 
RESULTS AND CONCLUSION: Intraoperative DSA showed overall 32 aneurysms had successful stenting and coil implantation. The operative effectiveness was 100%. Out of 32 aneurysms, 30 (94%) were completely embolized and 2 (6%) were partially embolized. All patients recovered well postoperatively. The average hospitalization time was 6.3 days. All the 32 individuals participated in a formal follow-up from 3-6 months and postoperative cerebral angiography found no intracranial bleeding, cerebral embolism or reoccurrence of aneurysm. Neuroform3 stent-assisted coil embolization is an effective and safe method with good biocompatibility in treatment of wide-necked anterior communicating artery aneurysm.

中国组织工程研究杂志出版内容重点：生物材料；骨生物材料; 口腔生物材料; 纳米材料; 缓释材料; 材料相容性；组织工程


全文链接：

Key words:  stents, embolism, aneurysm

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